Research has looked into how salivary flow is impacted following radiation therapy for Head and Neck Cancer. Salivary flow is very important, with a lack of saliva often causing oral health problems to develop. By looking at how salivary flow is impacted by radiation therapy, it can help professionals to improve treatment outcomes and overall oral health.
Recent research has looked into salivary flow in males and females following radiation therapy for Head and Neck cancer [1].
Salivary flow is very important, as a lack of saliva can result in numerous oral health problems developing. Therefore, studying this side effect of radiation therapy is very helpful.
The findings of this research will help to guide health professionals in providing oral health advice to patients getting radiation therapy.
Background
Many people are unaware of how saliva is a crucial part of our oral health. Saliva – also known as spit – is the clear liquid that is made by the glands in the mouth.
Saliva protects our mouth as we eat, chew, and talk. Additionally, it helps to counteract bad bacteria, and protect our tooth enamel.
However, reduced salivary flow, also known as hyposalivation – can increase the risk of tooth decay [2]. As teeth become decayed, cavities will eventually develop, and gums can become irritated.
The focus of this research was on patients receiving treatment for Head and Neck Cancer. This is the sixth most common type of cancer around the world, and impacts the lives of many [3].
One of the main treatments for Head and Neck cancer is radiation therapy. Radiation therapy involves using radiation to kill cancer cells. The researchers wanted to see how the salivary flow of test subjects responded following radiation therapy [1].
The Research
The research was conducted by a team from the University of Connecticut (UConn). Their findings were published in the Oral Diseases journal [1].
As discussed, the team wanted to find out how salivary flow impacted men and women following radiation therapy.
The research involved 572 patients, all of which had a diagnosis of Head and Neck cancer [1]. They were all due to receive radiation therapy as part of their treatment.
Prior to receiving the therapy, salivary flow was measured. Interestingly, it was found that women had reduced salivary flow at this point [1].
This is consistent with other research, with the difference in the size of the salivary glands between men and women often being seen as the cause of this [1].
The patients then went through radiation therapy. Then, six months later their salivary flow was measured again [1]. The researchers wanted to see if differences between males and females remained.
The measurements showed that the differences remained. Moreover, the difference was considered to be “significant” by the researchers – with the females having a much lower salivary flow compared to males [1].
A further test followed after a further year – representing 18 months after radiation therapy had been completed. The findings were consistent with the results from 6 months, with the difference between males and females still substantial [1].
Therefore, the researchers were able to conclude that females have a significantly lower salivary flow compared to males both before and after radiation therapy [1].
This means that females who undergo radiation therapy have a higher risk factor for oral health problems [1]. Therefore, this is an important consideration for health professionals.
What this means
These results will aid health professionals in the treatment and risk assessment of patients undergoing radiation therapy – especially in regards to their oral health.
Based on the results of this research, it seems that health professionals need to ensure women especially focus on stimulating the production of saliva where possible. It is crucial too that men do not become complacent.
This is backed up by the comments from Dr. Rajesh Lalla, who said that the results demonstrate that females “have significantly different ranges of normal salivary flow” compared to males [4].
Continuing, Lalla said that “having a very dry mouth can greatly affect quality of life and increase risk for several oral diseases” [4]. Therefore, this underlines the importance of avoiding dry mouth.
Overall, these findings will be helpful in advancing the understanding of the impact of radiation therapy on oral health. Hopefully, we will see an improvement in the treatment management of those with oral health problems – especially following radiation therapy.
Thinking points…
1) Stimulating saliva is very important for our oral health. If you have a dry mouth, then there are plenty of things you can try. These include sipping water throughout the day, sucking on ice cubes, chewing sugar-free gum, and if needed, using saliva substitutes. These are all practical ways of improving the production of saliva – which should boost your overall oral health!
2) Remember that attending a dental check-up regularly is crucial! At a dental check-up, a dentist will be able to take a thorough look at your mouth. They will look out for any problems, provide advice, and suggest treatment options if needed. It is advisable to attend a check-up at least once every six months. We recommend booking an appointment now!
What we offer at Savanna Dental
Savanna Dental is a dental clinic based in Calgary, Alberta, Canada. We provide our patients with a range of treatment options and advice, with the aim of improving oral health and boosting overall wellbeing!
We advise our patients to attend our Calgary-based dental clinic twice a year for a dental check-up. If any problems are detected, we have many treatments available. For instance, these include cavity fillings and root canals. To try and prevent problems, it is important to brush your teeth at least twice a day and floss regularly.
Here at Savanna Dental, we also have some cosmetic treatments available! These include dental implants, tooth whitening and Invisalign™! Our patients find that these treatments have a positive impact on their appearance, confidence and self-esteem.
In addition, the fees of our services at our Calgary dental clinic Savanna Dental are set in line with the Alberta Dental Fee Guide.
We would love you to visit our Savanna Dental clinic in Calgary! You can find out more about us by visiting our website https://savannadentalclinic.ca/!
References
[1] Lalla, R. V., Helgeson, E. S., Virk, K., Lu, H., Treister, N. S., Sollecito, T. P., Schmidt, B. L., Patton, L. L., Lin, A., & Brennan, M. T. (2024). Females have lower salivary flow than males, before and after radiation therapy for head/neck cancer. Oral Diseases. 15: 15068. DOI: https://doi.org/10.1111/odi.15068.
[2] Dos Santos Letieri, A., Siqueira, W. L., Solon-de-Mello, M., Masterson, D., Freitas-Fernandes, L. B., Valente, A. P., Ribeiro de Souza, I. P., Fidalgo, T. K., & Maia, L. C. (2022). A critical review on the association of hyposalivation and dental caries in children and adolescents. Archives of Oral Biology. 144 (105545). DOI: https://doi.org/10.1016/j.archoralbio.2022.105545.
[3] Guo, K., Xiao, W., Chen, X., Zhao, Z., Lin, Y., & Chen, G. (2021). Epidemiological Trends of Head and Neck Cancer: A Population-Based Study. Biomed Research International. 2021 (1). DOI: https://doi.org/10.1155/2021/1738932.
[4] Chandler, C. (2024). NIDCR-funded Study Finds Females Have Lower Salivary Flow Than Males. Available: https://today.uconn.edu/2024/08/nidcr-funded-study-finds-females-have-lower-salivary-flow-than-males/#. Last accessed: 6th September 2024.