Author: savannadental

Hypophosphatasia is a rare condition that affects the development of bones and teeth. Therefore, it causes several oral health problems, making early detection crucial. A research team has looked at cases of hypophosphatasia, and sought to find out how dentists can identify suspected cases of the condition at an earlier stage.

Hypophosphatasia is a rare condition that impacts the development of bones and teeth. It is a debilitating condition and causes lifelong problems for those with the condition.

Due to the impact on teeth, those with hypophosphatasia face oral health challenges from an early age and throughout their life. Therefore, there have been ongoing efforts to aid those with the condition.

Now, new research into the condition has presented findings that could help dentists in identifying suspected cases of hypophosphatasia earlier [1]. This is an exciting finding and will hopefully improve treatment outcomes for those with this condition.

What is Hypophosphatasia?

Hypophosphatasia is a rare skeletal disease which affects bones and teeth. It involves the abnormal development of the bones and teeth [2].

Hypophosphatasia is a serious condition and can cause fetal death. Some people won’t see any symptoms for several years. The earlier that the signs are spotted, the better.

The condition is caused by genetic changes to the ALPL gene [1]. It is possible for hypophosphatasia to run in families.

Those with hypophosphatasia typically have physical health symptoms like feeding and breathing problems in infancy, short stature, weak bones and short limbs [1].

Past research has underlined the oral health problems facing those with the condition. For example, one study found that when comparing those with hypophosphatasia and members of the general public, that those with hypophosphatasia had a higher chance of having severe gum disease and a higher number of teeth missing [3].

However, there have been positive developments in recent times. Enzyme replacement therapy has offered promise, with research finding that using this type of therapy can lessen the severity of oral manifestations of hypophosphatasia [4].

Therefore, having any additional research into this subject is highly desirable. By doing so, it can help support those with hypophosphatasia towards improved oral health.

The Research

The research was carried out by a team of researchers from Osaka University in Japan. Their findings have been published in the Scientific Reports journal [1].

The research involved studying Japanese patients with a diagnosis of hypophosphatasia. The researchers have carried out similar studies once every five years since 2013 [1].

This was the largest study yet on hypophosphatasia in terms of participants – with the researchers collecting data from 103 cases of hypophosphatasia across 30 clinics [1].

By having such a huge number of cases, the research team were able to break them down into two groups. One group whose symptoms involved only teeth – called the odonto-type disease, and those who had other symptoms, termed “non-odonto type disease” [1].

Clinical dental records were studied in order to identify common oral symptoms of the condition. Moreover, the researchers were particularly interested in seeing how the cases differed between the two groups.

When comparing the groups, they were looking at many different factors. Finding trends in these factors allowed them to make conclusions.

They found that those with odonto-type hypophosphatasia were more likely to lose their first teeth early [1]. This is a clear indication of hypophosphatasia, and with this type involving teeth, the link makes sense.

Those with the non-odonto-type disease were likelier to have tooth misalignment and tooth hypomineralization, which refers to enamel on the outside of the teeth softening [1]. This can make someone more prone to tooth decay.

Moreover, the researchers found that the non-odonto-type disease were also likelier to engage in poor oral habits like finger sucking and tongue thrusting [1].

Moreover, they were likelier to have problems with swallowing [1]. Therefore, those with the non-odonto-type disease faced more oral health problems.

The role of dentists

Dentists have an important role to play. Some people are unaware that dentists are also trained to look for the symptoms of various conditions. For example, dentists can identify the signs of oral cancer, such as tumors.

Furthermore, this extends to dentists being able to spot the signs of hypophosphatasia. Sometimes it will be dentists that are the first to notice this condition.

One of the study’s authors – Kazuhiko Nakano – said that the trends observed in this study “will be helpful for dentists who might come across patients with hypophosphatasia in their clinics” [5].

Furthermore, Nakano posited that “improved knowledge of the various ways this disease presents will lead to better diagnostic rates and earlier treatments for affected patients” [5].

Summary

Overall, the study showed that both types of hypophosphatasia cause oral health problems. However, the problems for those with the non-odonto-type version of hypophosphatasia had more difficulties [1].

Rena Okawa was the lead author of the study. Okawa mentioned that the team were “surprised to see big differences in oral manifestations between the two groups” [5].

With that said, it should be noted that both types are debilitating, and irrespective of the quantity of problems, the condition puts patients at high risk of oral health problems.

Research like this is very helpful and aids towards raising awareness and improved diagnostic rates. Hopefully these continuous efforts will result in improved treatment outcomes and quality of life for those with hypophosphatasia.

Thinking points…

1) As shown above, dentists have an important role to play with overall health. By examining your mouth, they can look out for the signs and symptoms of key illnesses and conditions. Therefore, we strongly recommend attending check-ups regularly. Check-ups ensure that a dentist can take a thorough look at your oral health and check for any warning signs of various conditions. We recommend booking an appointment now!

2) Do you know anyone with hypophosphatasia? If so, this article could be of interest to them. You could share this with them now! However, perhaps you’d never heard of this condition before? You could share this knowledge with friends and family, why not send them the link to this article now?

What we offer at Savanna Dental

Savanna Dental is a dental clinic based in Calgary, Alberta, Canada. We provide our patients with a range of treatment options and advice, with the aim of improving oral health and boosting overall wellbeing!

We advise our patients to attend our Calgary-based dental clinic twice a year for a dental check-up. If any problems are detected, we have many treatments available. For instance, these include cavity fillings and root canals. To try and prevent problems, it is important to brush your teeth at least twice a day and floss regularly.

Here at Savanna Dental, we also have some cosmetic treatments available! These include dental implants, tooth whitening and Invisalign™! Our patients find that these treatments have a positive impact on their appearance, confidence and self-esteem.

In addition, the fees of our services at our Calgary dental clinic Savanna Dental are set in line with the Alberta Dental Fee Guide.

We would love you to visit our Savanna Dental clinic in Calgary! You can find out more about us by visiting our website https://savannadentalclinic.ca/!

References

[1] Okawa, R., Kadota, T., Kurosaka, H., et al. (2025). Japanese nationwide dental survey of hypophosphatasia reveals novel oral manifestations. Scientific Reports. 15 (6743). DOI: https://doi.org/10.1038/s41598-025-91043-7.

[2] Genetic and Rare Diseases Information Center. (2025). Hypophosphatasia. Available: https://rarediseases.info.nih.gov/diseases/6734/hypophosphatasia. Last accessed: 14th March 2025.

[3] Weider, M., Schlagenhauf, U., & Seefried, L. (2022). Oral health status of adult hypophosphatasia patients: A cross-sectional study. Journal of Clinical Periodontology. 49 (12): p1253-1261. DOI: https://doi.org/10.1111/jcpe.13718.

[4] Smart, G., Jensen, E. D., Poirier, B., & Sethi, S. (2023). The impact of enzyme replacement therapy on the oral health manifestations of hypophosphatasia among children: a scoping review. European Archives of Paediatric Dentistry. 24: p429-440. DOI: https://doi.org/10.1007/s40368-023-00796-0.

[5] Osaka University. (2025). Hard evidence of soft teeth: the oral symptoms of hypophosphatasia. Available: https://www.asiaresearchnews.com/content/hard-evidence-soft-teeth-oral-symptoms-hypophosphatasia. Last accessed: 14th March 2025.

It is very important that children look after their oral health. With February marking National Children’s Dental Health Month, now is a great time for parents to think about the oral health of their children. There are several ways that parents can encourage strong oral hygiene, which can contribute towards strong oral health in the long-term.

February marks National Children’s Dental Health Month, which offers parents a chance to have a think about their children’s oral health [1].

Whether this is reviewing their diet, how much they brush, their oral hygiene, or anything else – this month provides an opportunity to review the oral health of children.

Oral health is crucial for children and can aid their wellbeing as they grow up. Parents have an important role to play in this.

About National Children’s Dental Health Month

Every February, the United States observes National Children’s Dental Health Month. The month intends to promote the benefits of good oral health in children.

The program actually began as a one-day event in 1941 [1]. By 1955, it became a week-long celebration. Then in 1981, the program became a month-long event. It has remained this way since.

The American Dental Association (ADA) sponsor the month [2]. The message behind the month has reached millions of people over the last few decades.

The ADA produce a range of resources and materials for children, including activity sheets, how-to guides, essay contests and many posters [2].

Why is children’s oral health so important?

The oral health of children is very important for numerous reasons. Overall, strong oral health can help to promote a lifetime of healthy teeth and gums, which aids overall health.

Oral health can impact multiple spheres of life for children – including physical, social, and emotional health [1]. Moreover, it also impacts their eating and speaking.

Tooth decay is the most common chronic condition in children [3]. In fact, half of children aged 6-9 have had at least one cavity in their mouth [3].

These issues are more pronounced in lower income households. For example, children aged 6 to 9 from lower income households are more than twice as likely (25%) to have untreated cavities than children from higher income households (10%) [4].

Research shows that poor oral health in children is linked to worse academic performance [5]. This is normally due to oral pain keeping them off school.

Moreover, in a concerning finding, children lose 34 million hours of school each year due to emergency dental care [5].

Perhaps the most important finding of all from past research is that good dental health enhances the quality of life of children, which underlines its significance [6].

How can parents help?

With the above in mind, it shows why it is so important for parents to help their children with their oral health. There are several ways that parents can do this.

Encouraging and instilling good oral health habits from a young age is important. At a minimum, children should be brushing their teeth twice per day with fluoridated toothpaste.

Brushing all surfaces of the teeth is important too. Missing part of the teeth leaves them vulnerable to tooth decay, which can result in cavities developing.

It can be advisable for parents to supervise their children’s toothbrushing until they can manage their own brushing.

If parents live in an area with fluoridated water, it is a good idea for their children to consume this. Water – whether fluoridated or not – should be consumed rather than soft drinks or juice.

Furthermore, avoiding sugary foods can also help to fight against decay. A healthy diet low in sugar and high in nutrients can result in better physical health too for children.

Attending regular visits to the dentist is also important. This underlines to children the importance of oral health, and it also allows a dentist to take a thorough look at their oral health.

Summary

Oral health is a very important aspect of overall health. The effort and resources placed onto this month underline how crucial oral health is!

Parents have an important role to play. By encouraging strong oral health habits from a young age, it helps to build the foundation for excellent oral health for life.

As discussed above, there are many ways that parents can help. This helps to contribute towards overall health, wellbeing and quality of life.

Thinking points…

1) While the oral health of children is very important, this shouldn’t detract from how vital oral health is for adults too. Therefore, remember to attend dental check-ups as an adult! These check-ups allow a dentist to review your oral health, provide advice, and suggest treatment if needed. If you have children, you could also take them with you, as this will set a good example. We recommend that you book an appointment now!

2) As discussed earlier, February is National Children’s Dental Health Month. Do you have children? If so, you could have a read through this article with them and discuss the importance of oral health. It should educate them and aid their overall oral health. Why not have a discussion now?

What we offer at Savanna Dental

Savanna Dental is a dental clinic based in Calgary, Alberta, Canada. We provide our patients with a range of treatment options and advice, with the aim of improving oral health and boosting overall wellbeing!

We advise our patients to attend our Calgary-based dental clinic twice a year for a dental check-up. If any problems are detected, we have many treatments available. For instance, these include cavity fillings and root canals. To try and prevent problems, it is important to brush your teeth at least twice a day and floss regularly.

Here at Savanna Dental, we also have some cosmetic treatments available! These include dental implants, tooth whitening and Invisalign™! Our patients find that these treatments have a positive impact on their appearance, confidence and self-esteem.

In addition, the fees of our services at our Calgary dental clinic Savanna Dental are set in line with the Alberta Dental Fee Guide.

We would love you to visit our Savanna Dental clinic in Calgary! You can find out more about us by visiting our website https://savannadentalclinic.ca/!

References

[1] McConnell, P. (2025). Tips for Parents to Encourage Healthy Smiles. Available: https://patch.com/wisconsin/appleton/tips-parents-encourage-healthy-smiles. Last accessed: 28th February 2025.

[2] American Dental Association. (2025). February is National Children’s Dental Health Month (NCDHM). Available: https://www.ada.org/resources/community-initiatives/national-childrens-dental-health-month. Last accessed: 28th February 2025.

[3] National Institute of Dental and Craniofacial Research. (2025). Dental Caries (Tooth Decay) in Children Ages 2 to 11 Years. Available: https://www.nidcr.nih.gov/research/data-statistics/dental-caries/children. Last accessed: 28th February 2025.

[4] Centers for Disease Control and Prevention. (2024). Oral Health Surveillance Report: Dental Caries, Tooth Retention, and Edentulism, United States, 2017–March 2020. Available: https://www.cdc.gov/oral-health/php/2024-oral-health-surveillance-report/index.html. Last accessed: 28th February 2025.

[5] Naavaal, S., & Kelekar, U. (2018). School Hours Lost Due to Acute/Unplanned Dental Care. Health Behavior and Policy Review. 5 (2): p66-73. DOI: http://dx.doi.org/10.14485/HBPR.5.2.7.

[6] Guarnizo-Herreno, C. C., & Wehby, G. L. (2013). Children’s Dental Health, School Performance and Psychosocial Well-Being. The Journal of Pediatrics. 161 (6): p1153-1159. DOI: https://doi.org/10.1016/j.jpeds.2012.05.025.

The results of a recent poll have produced some worrying statistics. Over 1,800 parents answered a poll about the oral health and hygiene habits of their children. While there were some positive findings, the results suggest that there is room for significant improvement in the oral hygiene habits of many children.

Children are facing dental issues on an increasing basis. While in the past issues such as cavities only affected adults, dental clinics are seeing an ever-increasing number of children present with tooth decay.

Many potential causes of this have been put forward, including poor diet, inadequate brushing, a lack of dental clinic visits, and scepticism of fluoride.

In fact, a new national poll has suggested that more than one in three children have faced problems like tooth decay and cavities over the past two years [1].

About the national poll

The C.S. Mott Children’s Hospital, which is part of the University of Michigan, commissioned a national poll based around children’s oral health [1].

The poll was conducted by Ipsos Public Affairs. In August 2024, a randomly selected group of with at least one child aged 1-17 were asked a series of questions [1].

The poll received responses from 1,801 parents, which represents a number that can provide useful insights into the oral health of children [1].

The poll asked parents questions pertaining to the oral health of their children. The results were quite concerning and provide an explanation for the growing dental issues in children.

Oral hygiene poll results

The first section of the poll focused on six oral hygiene practices. These refer to the daily activities a child should do to protect their teeth.

In arguably the most concerning finding, only 3 in 5 parents said that their child regularly brushes their teeth twice a day [1]. Toothbrushing twice a day should be a bear minimum, as irrespective of anything that happens throughout the day, at least this ensures a child’s teeth will receive protection from fluoride twice a day.

Moreover, when brushing, it is important to clean for at least two minutes, so that all areas of the mouth can be sufficiently cleaned. The results showed that only 59% of parents said their children brushes for at least two minutes [1].

Aside from brushing teeth twice a day, using a mouthwash or fluoride rinse throughout the day can be helpful. 22% of parents said that their children did this daily [1].

Eating sugary snacks is common in childhood. But something that can limit damage to the teeth is to rinse the mouth with water following consuming anything sugary, as this can help to regulate acid levels in the mouth. Just 15% of parents said that their children do this [1].

35% of adults said that their child cleans their tongue, with 23% saying that their child flosses [1]. While tongue cleaning and flossing isn’t essential in childhood, they should be encouraged, as they are important activities in adulthood.

So none of these six areas received particularly strong results. Only 20% of children according to the poll engage in 4-6 of these practices. Ideally this number would be significantly higher.

41% of children complete 2-3 practices, whilst 38% report 0-1 practices [1]. These results suggest that very few children are engaging in the recommended oral hygiene practices.

Dental problems poll results

The second part of the poll asked the parents about any dental problems that their child had experienced. Similar to the above, there were some worrying results.

36% of parents reported that their child had experienced dental problems relating to oral hygiene in the last two years [1]. Furthermore, this included cavities/tooth decay (29%), discolored/stained teeth (7%), tooth sensitivity (6%), and gum problems (3%) [1].

Interestingly, these results were directly linked to the oral hygiene practices mentioned earlier. 44% of children whose parents reported completing 0-1 practices had dental problems, compared to 31% for those completing 2-3 practices, and 28% for those performing 4-6 practices [1].

There were other findings too. 36% of parents said that they had noticed their child has bad breath [1]. This was especially prevalent in the group that engaged in 0-1 oral hygiene practices.

In some positive news, 85% of parents addressed the issue of bad breath, with interventions including going to the dentist, increasing the frequency of brushing, using mouthwash or changing their diet [1].

In terms of recent visits to the dentist, 89% of parents said their last visit to a dental clinic came within the past year [1]. This was a positive finding, with dental check-ups being crucial!

7% of parents said that the visit was between 1 and 2 years ago, and 4% said that their child’s last visit was over 2 years ago [1].

What does this mean?

The oral health of children is crucial. Good oral hygiene habits in childhood can set up a strong foundation for the future. Therefore, it is important that parents emphasize to their children the importance of looking after their teeth.

Completing the various hygiene practices outlined above can be helpful. Oral health also impacts physical health, which further underlines the importance of oral health for children.

Building oral hygiene practices into a daily routine can be helpful. Moreover, regular visits to a dental clinic for a check-up should be encouraged.

By looking after their teeth, it can help children to avoid oral pain, build oral hygiene skills for the future, and allow them to spend more time learning and having fun.

Thinking points…

1) Are you a parent? If so, remember the importance of following the six oral hygiene practices mentioned above. Make sure your child brushes their teeth twice a day for at least two minutes, cleans their tongue, flosses gently, uses mouthwash and rinses their mouth with water following sugary snacks. By following these practices, you can help their oral health!

2) Additionally, as a parent you can set a good example to your children by attending a dental clinic regularly for a check-up. By doing this, it underlines the importance of oral health to your children. You should attend a check-up at least once every six months. We recommend booking an appointment now!

What we offer at Savanna Dental

Savanna Dental is a dental clinic based in Calgary, Alberta, Canada. We provide our patients with a range of treatment options and advice, with the aim of improving oral health and boosting overall wellbeing!

We advise our patients to attend our Calgary-based dental clinic twice a year for a dental check-up. If any problems are detected, we have many treatments available. For instance, these include cavity fillings and root canals. To try and prevent problems, it is important to brush your teeth at least twice a day and floss regularly.

Here at Savanna Dental, we also have some cosmetic treatments available! These include dental implants, tooth whitening and Invisalign™! Our patients find that these treatments have a positive impact on their appearance, confidence and self-esteem.

In addition, the fees of our services at our Calgary dental clinic Savanna Dental are set in line with the Alberta Dental Fee Guide.

We would love you to visit our Savanna Dental clinic in Calgary! You can find out more about us by visiting our website https://savannadentalclinic.ca/!

References

[1] Mott Poll. (2025). Oral hygiene is key to healthy smiles. Available: https://mottpoll.org/reports/oral-hygiene-key-healthy-smiles. Last accessed: 14th February 2025.